oCelloScope - Automated Microbial Live-Cell Imaging and Analysis

Automatically acquire and analyze images of your bacterial cells, fungus and yeast with real-time microscopic kinetic data

Manufacturer: BioSense Solutions

ocelloscope introduction


Do you know how your microbial cells develop? 

Using the oCelloScope, get more information and insight about your cells with real-time kinetic data. The oCelloScope will automatically acquire and analyze images within standard microtiter plates, and will free up researchers' time, increasing sample throughput and delivering richer data. 

The oCelloScope is a unique live-cell imaging system for sensitive and detailed monitoring of biological growth and development. The oCelloScope system integrates 3 key features: 

  • Unique proprietary scanning technology, FluidScope™
  • Powerful image analysis software
  • Precision mechanical engineering

The 3 key features used together provide detailed information, enabling researchers to set up high-throughput testing and robust time-lapse studies. 

ocelloscope real time testing


 How can you benefit from live-cell image analysis with oCelloScope? 

By combining continuous real-time imaging and powerful image analysis software with oCelloScope: 

  • You will never miss a data point again
  • Capture and profile time dependent events
  • Analyze microbial growth and development
  • Visualize and validate the results with images and videos




  • 250 times more sensitive than a plate reader (OD)
  • Measure and visualize down to 5 x 103 CFU/ml
  • Growth kinetic MIC results in few hours Vs 16-20h using BMD
  • FluidScope™ technology scans a full 96-well plate in less than 3 minutes

Early Phase Morphology

  • Compare growth kinetic curves with images from each time-point
  • Discover microorganism adaptation strategies
  • Capture and quantify morphological changes over time
  • Spheroplasts, Filamentation, Co-aggregation, Fungal spore germination


  • Full flexibility - use your standard microtiter plates
  • You get full software package to use on multiple PCs
  • No expensive annual service contract
  • Competitive pricing. Rent or Purchase - just ask for a quotation


oCelloScope in Incubator1


oCelloScope Workflow

With oCelloScope and the powerful UniExplorer software your research is supported day and night


Make your experiment in any environment

  • oCelloScope fits inside your incubator or anaerobic chamber
  • Compatible with standard microtiter plates, from 6 to 96 wells




setup automated aquisition and analysis1




Setup automated acquisition and analysis

  • Easy-to-use user interface for simple and flexible setup of your experiment
  • Auto-focus and auto-illumination secures high quality data





Acquire images for as long as you like1



Acquire images for as long as you like

  • Automatically acquire images for hours, days, or weeks
  • Use UniExplorer's continue mode for running multiple long-term experiments simultaneously



View and analyze in real time1




View and Analyze in real-time

  • Follow you experiment in real-time with visualization of images and analysis
  • Get an instant overview of your full 96-well plate
  • Analyze single cells and mixed cultures







FluidScope™ scanning technology

oCelloScope is based on a unique optical scanning technology FluidScope™ combining optical techniques such as phase contrast, brightfield and confocal-like microscopy. 

Together with advanced image processing algorithims, the FluidScope™ technology provides: 

  • Fast scanning of a volume in the sample
  • Greater freedom of operation with multiple Z-layers acquired simultaneously
  • Detailed 3D information at a single cell level
  • Requires no pre-treatment, staining, or additional reagents




Measurement Specifications

Sample objects

 Most objects in (semi) transparent substances/liquid/agar can be analyzed, e.g.: 

  • Mammalian cells
  • Bacteria
  • Yeast
  • Fungi
  • Inorganic particles (crystals) 
Sample matrix  Liquid and agar
Detectable density (sample concentration)  From 103 objects/mL
Detectable object size  0.5 μm - 1 mm
Maximum scanning speed  2 minutes 36 seconds (96-wells)
Optical magnification  4x
Optical resolution  1.3 μm
Camera  5 Mpx, CCD, pixel size: 2.2 μm
Optical principle FluidScope™ (patent pending)

Environmental Specifications

Operating temperature   10 - 40ºC
Operating humidity  20 - 93% RH


Dimensions (D x W x H)  450 x 260 x 250 mm (with open lid: H = 550 mm)
 Weight  9.6 kg
Connectors  RJ45 (Ethernet)


oCelloScope Microbiology Applications

oCelloScope Publications

oCelloScope Brochure