100L Top Loading Steam Autoclave

Built for in-chamber steam generation or hooked to your existing house steam supply

SKU: 100L Top Loading Steam Autoclave


100L Top Loading Steam Autoclave

The Priorclave Top-Loading 100L can be built for in-chamber steam generation, hooked to your existing house steam supply, or configured to do both. It’s known for its fast heating and cooling—even with dense or heavy loads—and easy loading and unloading of bagged waste. The 100L is popular with community colleges and industrial labs, because it offers big capacity without the “big” autoclave.

Top-loading autoclaves like the 100L are the standard for lab work in Europe, and the #1 top-sellers for Priorclave UK worldwide because they are among the most space-efficient sterilizers available. They easily accommodate the tallest flasks, fermentors, and bioreactors, but cost one-third as much as a comparable front-loading autoclave—making them popular with life-science research labs and academic institutions. They’re also excellent for waste processing—after all, every trash can in your lab is a “top loader.”

Priorclave top-loading autoclaves are bench-height (regardless of capacity) and mounted on casters, making them easy to install, and ideal for flexible spaces and regularly reconfigured facilities. Paired with the Loadlite integrated electrically operated hoist, any load can be pulled or placed effortlessly.

Steam Source: Electrically generated in-chamber OR external generator
Operating Range:Up to 136°C, 2.2 Bar (277°F, 32 psi)
Working Dimensions:19.5” (496mm) diameter x 19.5” (496mm) deep
Chamber Material:Brushed grade 316L stainless steel
Door Material:Burnished grade 316L stainless steel


Priorclave top-loading autoclaves are built in the UK for years of trouble-free operation, even in the most adverse conditions. Their modular design is completely upgradable to meet your evolving needs. Each unit is designed for safe operation under all conditions, and fitted with the industry-favored Tactrol® 2 Control System. Priorclave autoclaves offer a 36-month limited parts and labor warranty, 20-year pressure vessel warranty, and unlimited technical support.


At Priorclave, the safety of your staff and students comes first. Our Quickseal 2 door, with Permission-based Door Release, is fitted with thermal and pressure locks to prevent opening at load temperatures above 80°C (176°F) and pressures above 0.2 Bar (2.9 psi) (as per BS 2646). The door is also fitted with a Redundant Safety Gate, so that any residual pressure can safely escape before the door can move freely (in accordance with the UK Health and Safety Executive’s note PM73). All units come with a Pressure Safety Valve set to 2.5 Bar (36.3 psi) and a 150°C (302°F) thermal cut out (per BS 6759); selected external panels and surfaces are thermally insulated.

Priorclave is the only manufacturer offering the same fully featured programmable control system on every model, from the smallest laboratory benchtop sterilizer to the largest industrial pass-through unit. The Tactrol 2 system puts every operating parameter within your control, with no re-training required as you move from one unit to another. Using our Tactrol 2 Control System, operators can limit user access to specific pre-programmed, validated cycles, via fail-safe one-button start or key switch activation. Program modifications are likewise key switch or password protected.

All Priorclave autoclaves comply with current US, Canada, UK, and EU safety regulations. They are manufactured under an ISO 9001:2008 quality management system in our UKAS-accredited facility. Our autoclaves and control systems are ETL listed and EMC certified, and feature ASME-stamped pressure vessels. These pressure vessels are manufactured entirely in-house, and tested to 1.5 times their maximum working pressure. They have full insurance approval for pressure vessel design and construction and are CE Marked under the Pressure Equipment Directive PD5500:2000 Cat 3, Certificate Number SS42059010-2 Rev 1. They also conform to the general requirements of BS 2646 and are CE Marked for BS EN61010-2-41, Low Voltage and Electromagnetic Compatibility.

Top-Loading 100L Standard Features:

  • Quickseal 2 Single Action Lid Closure System
  • Permission-based Lid Release
  • Thermostatic Air Purge Valve
  • Low Water Cut Out (on models with in-chamber steam generation)
  • Electrically Operated Vent Valve
  • Fully Programmable Tactrol® 2 Control System
  • Automatic Timed Freesteaming
  • Assisted Load Cooling
  • Media Warming and Delayed Start
  • Chamber Pressure Gauge
  • Thermocouple Entry and Test Ports
  • 316L Stainless Steel Chamber and Door
  • Two Stainless Steel Loading Baskets
  • Caster mounted for ease of positioning and service
  • Biomaster Antimicrobial Surfaces
  • Reliable water and energy savings


  • Tactrol 5 Program Memory
  • Tactrol 10 Program Memory
  • Upgrade Tactrol 5 to Tactrol 10 Program Memory
  • Tactrol Self-Monitoring System
  • Tactrol Plain-Paper Printer
  • Setting Lock Key Switch (standard with any Tactrol memory unit)
  • Pulsed Free Steaming
  • Load Sensed Process Timing
  • Automatic Water Fill System (models with in-chamber steam generation only)
  • Water Softener
  • Purified Water Level Sensor (models with in-chamber steam generation only)
  • Stainless Steel Pipework
  • Dual Electric & Steam Heating
  • Clean Steam Generation
  • Air Intake Filter System
  • Exhaust Filtration System
  • Air Ballast System for Accelerated Liquid Cooling (with or without external air supply)
  • Load Temperature Monitor
  • Chamber Pressure Monitor
  • Armored Wandering Probe
  • External USB Port (included in North American models)
  • Combined Pre-Cycle Vacuum & Vacuum Cooling
  • Post-Cycle Vacuum Drying
  • Automatic Cycle Repeat
  • Stainless Steel Loading Basket
  • Stainless Steel Waste Container
  • Loading Hoist
  • Drain Condenser
  • Two-Year Spares Kit
  • Three-Year Spares Kit
  • IQ/OQ/PQ Documentation

Technical data

Working Volume100 liters
Operating RangeUp to 136°C, 2.2 Bar (277°F, 32 psi)
Loading FormatTop
Loading Height29.7″ (755mm)
HeatingInternal Electrical OR House Steam Source
Heat Input11.2kW/internal OR 1.2kW/house (Three phase)o
Working Dimensions diameter x depth19.5” x 19.5” (496mm x 496mm)
Outside Dimensions w x d x h26” x 33.1” x 33.1” (660mm x 840mm x 840mm)
Floor Weight (unloaded)324.1lbs (147Kg)
Minimum Installation w x d x h (and Door Swing)38″ x 45.1″ x 55.1″ (965mm x 1146mm x 1400mm) including Door Swing

Ordering info

100L Top Loading Steam Autoclave

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Laboratory Autoclave Video Looks at the Priorclave Brand
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